Online Dissolution Testers – UV/Vis System

dissolution testers

ERWEKA dissolution testers with online systems are the perfect, semi-automatic solutions for dissolution testing with automated UV/VIS online analyses.

The DT 950 with the integrated, automated ASS-9 sampling station transports freshly sampled media directly to the UV/VIS analysis device (several brands available). There, the samples can be measured and the results  stored within our advanced Disso.NET dissolution software.

ERWEKA offers different types of UV/VIS analysis devices, such as the Shimadzu 1900i, the Analytic Jena Specord 210/8 or the Agilent Cary 8454. All combined with our dissolution tester DT 950 and a peristaltic pump IPC 8 and all controlled by the Disso.NET PC software.

Download the Online System Spec Sheet here.

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Reliable Operation

With the standard ERWEKA 8-channel peristaltic pump IPC 8 the sample is taken from the dissolution testers via a USP/EP compliant sampling station with stainless steel sampling tubes and is then injected to the flow-through cells of the  spectrophotometer. After analysis, the sample is transferred back to the test vessel.

The Disso.net software not only offers a compact analytical report (default report with all relevant data), but also shows method data, calibration data and raw data.

Dissolution UV-Vis system

Disso.Net Software – Software for Dissolutions Testers

The ERWEKA Disso.NET software is the perfect 21 CFR Part 11 compliant companion to our dissolution systems. The software provides support for all test methods manageable with the ERWEKA DT dissolution testers as well as the automated RoboDis II.

Disso.NET helps you with standard dissolution jobs, handles qualifying tasks and offers control over each single function of the connected devices (e. g. dissolution tester, UV-Vis spectrophotometer or HPLC analysis unit). Our audit trail generates detailed protocols of all events and times. The software additionally includes an easy-to-use editor for comfortable programming of the dissolution methods (for highest repeatability). After finishing the dissolution test, Disso.NET generates comprehensive reports (as PDF-files) with your corporate logo and/or exports the results (e. g. in XML format).

dissolution software

Technical Details

Dissolution Tester:ERWEKA DT 950
Pumps:8-channel peristaltic pump IPC 8. Pump tubing is made of verderprene to prevent absorption. Via the serial RS 232 interface the pump is controlled from the external PC
Spectrophotometers:Agilent, Jena or Shimadzu UV/Vis with Microsoft Windows-based software Disso.net by ERWEKA
System Control:ERWEKA Disso.net software: Windows based, CFR 21/11 compliant. ERWEKA driver to connect and control ERWKA DT dissolution testers
System Tubing:fluoropolymer system tubing 3.0 mm
Computer:Brand name PC, operating system Microsoft Windows 10
CuvettesCuvettes for UV/VIS spectrophotometers with fluoropolymer tubing (0.8 mm o.d.) and screw fittings are available with various path length (1 mm, 2 mm, 5 mm, 10 mm)

Options

Connection and drivers to the following spectrophotometers:Shimadzu 1900 double beam including 8 position cell changer
Agilent 8454 including 8 position cell changer
Analytic Jena Specord 210/8
CuvettesCuvettes for UV-VIS Spectrophotometers with fluoropolymer tubing (0.1 – 0.5 mm o.d.) and screw fittings are available with various path length (1 mm, 2 mm, 5 mm, 10 mm)
IQ/OQ/PV:IQ/OQ/PV documents are available/OQ/PV service is available
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